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| NS2-3 protease ： ウィキペディア英語版 |
NS2-3 protease
NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.
== Background about Hepatitis C ==
Hepatitis C affects 170 million people around the world which includes 1.4 million people living in the U.S. Most of the people infected with this virus live in third-world countries which often tend to have poor sterilization of medical equipment, a common source of HCV infection. Education also plays a big part as a vast majority of people don’t have access to the information about the virus, how it spreads and infects11. Hepatitis C can enter human body through many ways which include sexual intercourse, blood transfusion and via HCV infected needles. HCV infection can lead to cirrhosis and liver cancer if interferon treatment fails.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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